We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

Plants and their pollinators form complex interaction networks. Within these networks, species differ widely in the number of species they interact with.

In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.

S.S. Kolipaka’s thesis questions and investigates the survival prospects of reintroduced tigers and their offspring’s in the human dominated landscape of Panna tiger reserve in India.

Promotor: Prof.dr. P.G.L Klinkhamer, Co-promotor: K. Vrieling

Promotor: S.M. Verduyn Lunel, Co-promotoren: M.F.E. de Jeu, S.D. Silvestrov

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.

In this thesis, we present new laboratory data of interstellar dust analogues.

In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.

Decentralized plug and play systems for energy production are the future picture of our society. Artificial photosynthetic systems are used for this purpose.

Promotor: M. Franx, Co-Promotor: I.F. Labbé

Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.

This thesis investigates how galaxies form and what diversifies the evolutionary histories of galaxies.

Promotor: Prof.dr. J.W.M. Frenken

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.

Promotor: Prof.dr. E. Bouwman, Co-Promotor: S. Bonnet

LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.

Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.

This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…

Promotores: J. Kok, M. Chaudron (Chalmers University)

Possible improvements for the assessment of abiotic depletion in LCA.

Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.

Promotor: G.R. de Snoo, Co-promotor: H.H. de Iongh, C.J.M. Musters

An important part of the SCS specialisation is the internship period. Students will get the opportunity to get to know the field and to apply what they have learned during the courses.

M. Danhof, Co-promotores: J. Freijer, A. Yassen

Due to the almost complete disappearance of the archive of the Old Dutch West India Company (WIC, 1621-1674) not much is known about the ships and crews of this company. In this project we start the reconstruction of this basic information making use of new digital humanities techniques to extract this…

De Universiteit Leiden staat midden in de maatschappij en wil bijdragen aan een duurzame samenleving. Verduurzaming van gebouwen levert een bijdrage aan Nederlandse en Europese milieunormen. De Universiteit Leiden houdt daar in al haar bouwprojecten rekening mee.

Promotor: W.Th.F. den Hollander

In this thesis, we study travelling waves in stochastic reaction-diffusion equations. We extend techniques from the deterministic theory for travelling waves to apply to the stochastic version, which allows us to compute the stochastic wave speed and shape, and draw conclusions on the stability of the…

Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf

Promotores: H.W. Lenstra, B. Erez, Co-promotor: L. Taelman

Promotor: Prof.dr. C.U. Keller

In my thesis I study Majorana fermions from three different perspectives. The first one corresponds to non-interacting Majorana fermions that, however, pose non-trivial topological properties. The second one corresponds to strongly interacting Majoranas and the third to relic neutrinos. No one knows…

The work described in this thesis focuses on the development of linear or cyclized peptide probes against protein N-methyltransferases to characterize their specific binding behavior, providing further binding details for inhibitory activity study.

We describe certain birational modifications of nodal relative curves over a regular base of arbitrary dimension.

This thesis examines silicon pore optics (SPO), a technology that exploits silicon wafers from the semiconductor industry to create extremely high quality X-ray optics, by studying its manufacturing process, applications, and prospects.

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

The Minor in Business Administration teaches business knowledge and skills that are important for your future career.

Om studenten beter te betrekken bij ons onderwijs en veeleisend te helpen bij het succesvol afronden van hun studie, gaat dit team uitwerken welke voorzieningen hiervoor opgezet moeten worden en welke randvoorwaarden daarvoor nodig zijn.

Een van de facultaire ambities vanuit de midterm review is om diversiteit en inclusie te verbeteren in ons onderwijs.

The thesis describes experimental steps towards reduction of friction on the macroscopic scale by scenarios of thermo- and superlubricity well-known on the nanoscale.

Mechanical interactions between cells and their environment play an important role in many biological processes.

Promotor: A. Doelman, Co-promotor: M.F.E. de Jeu

Promotor: Prof.dr. P. Stevenhagen, Co-Promotor: J.H. Evertse

In this thesis we push the boundaries of high-resolution imaging at radio frequencies between 100 and 200 MHz. Using the International LOFAR Telescope that spans across Europe we achieve sub-arcsecond angular resolution.

Optical cavities are useful tools to enhance the interaction between light and matter, which is important to make good quantum emitters. However, it turns out that the cavities themselves (without any quantum emitters) are already interesting objects to study.

Integrating life cycle assessment (LCA) with life cycle costing (LCC) offers the opportunity to simultaneously analyze the environmental and economic aspects of product alternatives, for the integration of which a unified computational has been proposed by Heijungs et al. (2013) [1]. The project aims…

The Economics and Governance specialisation of the Master in Public Administration teaches you to formulate problem-solving approaches to concrete policy issues found at the intersection between economics and public administration. This specialisation is a unique joint offering of the Department of…

In Zuid-Afrika zijn ongelijkheid en geweld de twee grootste problemen. Waar komen die problemen vandaan? Misschien hangen ze samen met rivaliserende groepen, misschien met economische factoren, met overheidsbeleid of met alle drie tegelijk. Om maatschappelijke problemen te begrijpen, is het belangrijk…