1,929 zoekresultaten voor “part 1521 1990 disease women” in de Publieke website
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Refined tautological relations on moduli spaces of curves
The key purpose of this project is to study tautological relations on the level of closed differential forms or even integral cochains (i.e. we don't take classes in cohomology).
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Revealing the nature of new low-frequency radio source populations
It has now been well established that shocks and turbulent motions in the intra-cluster medium (ICM) generated through cluster mergers can produce large-scale synchrotron emission.
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Laboratory studies of Water Ice in Space
Astronomical observations of cold regions in the universe show a rich inventory of ices. Part of these ices may end up on planets like our own, but in that journey they will be exposed to considerable amounts of radiation.
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Adsorption and catalysis on Pt and Pd monolayer-modified Pt single crystal electrodes
The focus throughout this thesis will be on gathering fundamental studies of the detailed structure and composition of the electrode/electrolyte interface effect on the rate and mechanism of key electrocatalytic reactions.
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Inhibitor Selectivity: Profiling and Prediction
Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.
- About this minor
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Nieuw project om ziekte van Alzheimer te bestuderen
Onderzoekers van de Universiteit Leiden gaan een nieuwe manier ontwikkelen om de biomarkers van de ziekte van Alzheimer te bestuderen. De aanpak focust zich op de moleculaire boodschappers van de cellen. Het project, geleid door Thomas Hankemeier en gecoördineerd door Yuliya Shakalisava (Leiden Academic…
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Deze elf Leidse bètaonderzoekers behoren tot de meest geciteerden ter wereld
Elf onderzoekers van de faculteit Wiskunde en Natuurwetenschappen staan op de 2021 Highly Cited Researchers-lijst van Clarivate Analytics. Slechts 0,1 procent van de wereldwijde onderzoekers komt in deze lijst voor, waarmee ze dus letterlijk één uit duizend zijn.
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Urbanization in Indonesia and Its Impact on Non-communicable Diseases
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Aortic valve disease: multimodality imaging for risk stratification and evaluation of therapy
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in acute myocardial infarction and the assessment of valvular heart disease
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Targeting autoimmunity in renal diseases: focus on neutrophil extracellular traps and autoreactive B-cells
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Advanced tools and methods for modeling cardiovascular disease using human pluripotent stem cells
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Genetic and clinical pharmacology studies in GBA1-associated Parkinson's disease
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Multi-modality imaging in ischemic heart disease, arrhythmia and cardiac-mechanics
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Based Pituitary Care, implementing Value Based Health Care in a rare disease
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Optimising neonatal management of haemolytic disease of the foetus and newborn
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closer look: Non-invasive tools for in-depth characterisation of vulvar diseases
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pharmacology of antimicrobials, towards optimized treatment of infectious diseases in hospitalized patients
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Therapeutic neovascularization for peripheral arterial disease; in vivo models and potential therapeutic factors
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to predictive modeling: cerebrovascular events and chronic kidney disease
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Synthesis of oligosaccharide libraries from GBS capsular polysaccharides for structure-based selection of vaccine candidates
Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.
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elderly in clinical trials: how to define preclinical Alzheimer’s Disease for clinical trial participation
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Remodeling, Myocardial Function and Risk Stratification in Cardiovascular Disease
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autoantibody-positive and autoantibody- negative rheumatoid arthritis during the disease course
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microbiota transplantation and dietary interventions in Inflammatory Bowel Disease; efficacy and challenges for the future
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A joint evaluation of local and systemic disease activity in treated-to- target rheumatoid arthritis
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Unraveling the broad NOTCH3-associated small vessel disease spectrum: from CADASIL to non-penetrance
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Multimodality Imaging in Coronary Artery Disease: Plaque Characterization, Computational Haemodynamic Simulation and Risk Stratification
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Specifiek eiwit in de hoofdrol bij ziekte van Parkinson
Met elektronspins hebben natuurkundigen het bindingsproces onderzocht van het eiwit α-synucleïne, dat wordt geassocieerd met de ziekte van Parkinson. Wat blijkt is dat het eiwit op een verrassend efficiënte manier bindt aan een hersenmembraan. Met deze in Leiden ontwikkelde methode hebben de onderzoekers…
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Gender and Agency in Careers: The Work-lIfe Experiences of Women Employed by Japanese and South Korean Firms
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Towards the development of synthetic vaccines against tuberculosis
The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.
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Health, Ageing and Society (Msc)
Discover the master program Health, Ageing and Scoiety at Leiden University and contribute to a future proof health care system. Read more.
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Student for a Day Security Studies
Studievoorlichting
- Oortlezing
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Instituut Biologie Leiden
De natuur is een onuitputtelijke inspiratiebron voor de wetenschappers van het Instituut Biologie Leiden (IBL). Vanuit het streven naar fundamenteel begrip van de natuur zoeken zij naar oplossingen op het gebied van gezondheid en behoud van de biodiversiteit. Het thema van het instituut is ‘Harnessing…
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The innate immune response against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf
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Quantitative pharmacological modelling for optimizing treatment of sepsis
Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…
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Functional analysis of agrobacterium tumefaciens virulence protein VirD5
Supervisor: P.J.J. Hooykaas
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Parkinson’s protein α-synuclein: membrane interactions and fibril structure
The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.
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PI3K signaling and adherens junctions in invasive lobular breast cancer
Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.
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Electrical and magnetic properties of ferritin: electron transport phenomena and electron paramagnetic resonance
Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.
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Pharmaceutical Aspects of Subvisible Particles in Protein Formulations
Promotor: W. Jiskoot, Co-promotor: A. Hawe
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Discovery of novel inhibitors to investigate diacylglycerol lipases and α/β hydrolase domain 16A
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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The road to insurmountability: Novel avenues to better target CC Chemokine receptors
This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.
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Image analysis for gene expression based phenotype characterization in yeast cells
Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek
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Phenotypic screening with 3D cell-based assays
Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.
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Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink
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Modulation of leukocyte homeostasis in atherosclerosis
Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.