1,041 zoekresultaten voor “non function” in de Publieke website
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The impact of climate variability on the ecology of a lion (Panthera leo Linnaeus 1758) population and lion livestock conflicts in the Amboseli
Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Co-promotor: H.H. de Iongh
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Unconditionally secure cryptographic protocols from coding-theoretic primitives
This dissertation presents new cryptographic protocols, which can be divided into two families.
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Synthesis of Ribitol Phosphate based Wall Teichoic acids
Antibiotic resistance, caused by widespread use of antibiotics, leads to bacterial infections that are difficult, if not impossible, to treat and is a major worldwide health concern.
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A fixed point approach towards stability of delay differential equations with applications to neural networks
Promotor: S.M. Verduyn Lunel, Co-Promotor: O.W. van Gaans
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Giant barrel sponges in diverse habitats: a story about the metabolome
Marine sponges are important members of reef ecosystems, as they play ecological roles that are essential for the health of the reef.
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RAISE Onderzoek
Het doel van het RAISE Onderzoek is om te onderzoeken hoe veerkrachtige mensen omgaan met stress. We kijken specifiek naar hoe belangrijke biologische systemen, zoals de HPA-as en het immuunsysteem, samenwerken met de hersenen en de sociale omgeving om veerkrachtig functioneren na moeilijkheden in de…
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Semigroups on Spaces of Measures
Promotor: S.M. Verduyn Lunel, Co-promotor: S.C. Hille
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Chemical tools to study lipid signaling
Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.
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Group benefits from genomic instability: a tale of antibiotic warriors in Streptomyces
Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.
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Split Jacobians and Lower Bounds on Heights
This thesis deals with properties of Jacobians of genus two curves that cover elliptic curves.
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Gene networks-based mechanistic assessment of drug-induced organ toxicity: a focus on liver and kidney
Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.
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Biomimetic models of [NiFe] hydrogenase for electrocatalytic hydrogen evolution
The growing demand of energy indicates that global energy resources in the form of fossil fuels will not be sufficient in the future. In order to solve potential future energy problems development of a sustainable hydrogen economy is highly desirable.
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Molecular engineering of plant development using Agrobacterium-mediated protein translocation
Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa
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Substrate adaptability of β-lactamase
The research aims to explore the evolutionary adaptability of enzymes and the impact of temperature on protein evolution pathways, using M. tuberculosis β-lactamase BlaC as the object of study. Enzymes inherently embody a delicate balance between activity and stability, and the acquisition of new enzymatic…
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Agenda dynamics in the European Union : the interaction between the European Council and the European Commission in the policy domain of organized
The European Council and the European Commission have a similar role in agenda setting. Both place issues on the EU agenda. However, these institutions have distinct designs. They have different political attributes (the European Council has considerably more political authority) and information-processing…
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Towards automated identification of metabolites using mass spectral trees
Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Single-molecule fluorescence in sequence space
The sequence-dependence of biomolecular interactions involving nucleic acids and proteins is essential for numerous processes inside the cell. Insights into the underlying molecular mechanisms have been obtained using various biochemical and biophysical methods on two different levels — bulk and sin…
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Reasoning about object-oriented programs: from classes to interfaces
Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…
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Affinity-based profiling of the adenosine receptors
The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
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Histone-DNA assemblies in archaea. Shaping the genome on the edge of life
All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).
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The developing infant gut microbiota: mathematical predictions of the effects of oligosaccharides
A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.
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Development of new chemical tools to study the cannabinoid receptor type 2
The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.
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Jean Monnet Chair of Moritz Jesse
Moritz Jesse has been awarded a Jean Monnet Chair by the European Commission. In his MIND-EU Project he will focus on a coherent way to teach Migration, Integration, and Non-Discrimination at Leiden Law School at bachelor and master level.
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Christa Tobler spreekt over indirecte discriminatie in Vilnius
Op 13 juni sprak Christa Tobler over indirecte discriminatie op de Vilnius Gediminas Technische Universiteit in Litouwen.
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Publicatie: Woodcuts as Reading Guides. How Images Shaped Knowledge Transmission in Medical-Astrological Books in Dutch (1500-1550)
In the first half of the sixteenth century, the Low Countries saw the rise of a lively market for practical and instructive books that targeted non-specialist readers. This study shows how woodcuts in vernacular books on medicine and astrology fulfilled important rhetorical functions in knowledge communication.…
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Development of highly accurate density functionals for H2 dissociation on transition metals
Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).
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Non-Textual Evidence in International Criminal Prosecutions
Promotie
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Non-invasive assessment of human brown adipose tissue
Promotie
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Non-Abelian Metamaterials: Emergent computing and memory
Promotie
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Prediction of spatial-temporal brain drug distribution with a novel mathematical model
A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.
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Towards a single-molecule FRET study of Frauenfelder's nonexponential rebinding of CO in myoglobin
Early time-resolved experiments by Frauenfelder on the ensemble of the kinetic rebinding of CO to myoglobin molecules resulted in a stretched exponential relaxa-tion due to a very large spread of the reaction rates of individual molecules.
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Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgery
Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst
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Inverse Jacobian and related topics for certain superelliptic curves
To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.
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The formation of complex organic molecules in dense clouds-Sweet results from laboratory
Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.
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Synthetic, Physical and Computational Chemistry of Propeller-shaped Polycyclic Aromatic Hydrocarbons
This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…
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Functions and biosynthesis of a tip-associated glycan in Streptomyces
Promotie
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Not to Detain: A Functional Approach to Non-State Armed Groups’ Activities in Non-International Armed Conflicts
Promotie
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Voormalig premier van Aruba, Mike Eman, geeft lezing aan het Europa Instituut
Op woensdag 13 februari verzorgde Mike Eman, voormalig premier van Aruba, een lezing over de relatie tussen Aruba, het Koninkrijk der Nederlanden en de Europese Unie. Hij sprak over de constitutionele positie van Aruba binnen het Koninkrijk in het licht van Unierecht en de toekomstige relatie met de…
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Samenwerking in de praktijk
Door samen te werken met externe maatschappelijke partners vindt de kennis van onze wetenschappers zijn weg naar de maatschappij.
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Transport coefficients and low energy excitations of a strongly interacting holographic fluid
In this thesis, classes of strongly interacting quantum field theories, have been studied.
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Optical cavities and quantum emitters
Optical cavities are useful tools to enhance the interaction between light and matter, which is important to make good quantum emitters. However, it turns out that the cavities themselves (without any quantum emitters) are already interesting objects to study.
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Arbeidsmarkt
En dan ga je als afgestudeerd film-of literatuurwetenschapper aan de slag! Hou je ervan om te adviseren? Zoek je een baan waarbij communicatie centraal staat? Of geef je liever les? Er is veel mogelijk met een diploma Film- en literatuurwetenschap op zak.
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Succesvolle ‘Law and Society’ conferentie in Mexico City voor Moritz Jesse
Dr. Moritz Jesse, universitair hoofddocent bij het Europa Instituut, presenteerde zijn paper Building Bridges or Erecting Walls? – The Application of Equal Treatment and Non-Discrimination in Europe ‘ tijdens de jaarlijkse bijeenkomst van de Vereniging voor Recht en Samenleving.
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Activity-Based Proteasome Profiling
Promotor: Prof.dr. H.S. Overkleeft
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Refined tautological relations on moduli spaces of curves
The key purpose of this project is to study tautological relations on the level of closed differential forms or even integral cochains (i.e. we don't take classes in cohomology).
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Global distribution patterns of distinct mycorrhizal types and ecological drivers of these patterns
What are the global relationships between environmental conditions and abundance of distinct types of mycorrhizal fungi in soil and plant roots?
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Monsters in the Deep: Using simulations to understand the excess baryonic mass in the centres of high-mass, early-type galaxies
This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…
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The Interactions of Human Mobility and Farming Systems and Impacts on Biodiversity and Soil Quality in the Western Highlands of Cameroon
Promotors: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Prof.dr.ir. H.H. de Iongh