Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…

Evolution acts via mutations in amino acid sequences. Substitution of essential amino acids leads to a nonfunctional protein. l.

Onderwijs voor nieuwsgierige en ambitieuze studenten die meer uit hun studie willen halen!

The studies in this thesis are focused on the physical effects in the flat band materials. The results contain the discovery of strong enhancement of RKKY spin-spin interactions with specific geometric arrangement and dynamical generation of excitonic order parameter with high magnitude.

Promotor: A. Achúcarro, Co-Promotor: G.A. Palma

Triplet superconductivity refers to a condensate of equal-spin Cooper pairs (pairs of electrons with equal spin).

Cardiovascular diseases are still a major concern for the global health.

Promotores: Prof.dr. J. Schaye, Prof.dr. S.D.M. White (MPA Garching)

The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.

My PhD research is devoted to studies of the conjectural cluster-algebraic symmetry in the theory of topological string, which is the simplest, however already non-trivial sector in the theory of string.

This thesis introduces the concept of

Promotor: Prof.dr. J. Kuiper

The Vallesian, 11.1-9 Ma, was a special time in the Vallès-Penedes basin near Barcelona, where a biodiversity hotspot existed. Europe had a subtropical climate, with rhinos, forest giraffes, lions, hyenas, flying squirrels and primates.

A large diversity of exoplanetary systems has been found, but it is still unclear what drives this diversity.

Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea

Promotor: P. T. de Zeeuw, Co-promotor: N. Neumayer; G. van de Ven

Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.

The work presented in this thesis is based on ALMA surveys of protoplanetary disks in three star-forming regions: Lupus, OMC-2, and NGC 2024.

Promotor: E. Bouwman, Co-promotor: S. Bonnet

Molecular materials have been a subject of interest in fundamental research and applications for decades, and have been studied as bulk crystals, (thin) films and as individual molecules, due to the large variety in their properties. This dissertation explores pentacene crystals near the two-dimensional…

Development of GHG calculator for bio-electricity and heat.

Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman

On the largest scale, the Universe resembles a cosmic spiderweb. Most galaxies coexist in small groups within the threads of this web. At the nodes of the threads are enormous groups of galaxies forming the largest structures in the universe still held together by gravity: clusters of galaxies.

Promotores: S.F. Portegies Zwart, E. M. Rossi

In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.

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African oral literatures, new media and technologies: challenges for research and documentation

Veel handgeschreven en geïllustreerde archieven bevatten een schat aan informatie, maar worden weinig bestudeerd vanwege hun complexe en door computers moeilijk te ontcijferen inhoud. Het doel van dit project is een digitale omgeving te ontwikkelen die hier een oplossing voor biedt, en die de heterogene…

Participants in this course will learn to support student teachers and new colleagues in their professional development as teachers, with particular emphasis on the context of bilingual or international education, as in the ICLON World Teachers Programme (WTP).

A critical look at the impact assessment modelling of metals in Life Cycle Impact Assessment and improvement options.

A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.

Promotor: E.F. Smets, Co-promotor: J. Geml

Carbon dioxide capture and utilization technologies are necessary to create a truly circular economy. The electrochemical reduction of carbon dioxide to formate is an appealing carbon utilization method as it can be performed at room temperature and pressure, it only requires two electrons, and it has…

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf

One of the most important correlation functions in physics, especially in cosmology, is the energy density, which describes how much energy is present at each point in spacetime due to matter fields. A key contribution to the energy density of the primordial universe comes from gravitational waves (GWs),…

Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken

The CC chemokine receptor 2 (CCR2), a member of the G protein-coupled receptor (GPCR) superfamily, is widely involved in autoimmune and inflammatory diseases. However, no drugs for this receptor have made it to the pharmaceutical market yet.

Promotores: J. Zaanen, A. Parnachev

Promotor: W.Th.F. den Hollander, Co-promotor: F.R. Nardi

This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.

Galaxies in the local Universe fall into two main categories of spirals and ellipticals. In this Thesis, we explore the structural evolution of galaxies into this bimodal distribution.

Promotor: V. Vitelli, Co-promotor: J. Paulose

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

Promotor: R. Cramer

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

The spindle-assembly checkpoint (SAC) is a safety mechanism which secures accurate chromosome segregation during mitosis.

In this Ph.D. thesis we study the interaction of low energy electrons with thin materials, namely layered materials (graphene, hexagonal boron nitride, molybdenum disulfide) and organic films. At these low energies the quantum mechanical wavelength of the electron wave function is in the order of a…

The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.