This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.

Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

Promotor: P. T. de Zeeuw, Co-promotor: N. Neumayer; G. van de Ven

The expedition commanded by Nicolas Baudin to Tenerife, Mauritius, Australia, Timor and South Africa in 1800-1804 is fully researched in regard to ornithology.

This PhD-thesis presents a study on micron-sized particles, so-called colloids. By controlling the chemical and physical properties of these particles, such as the interparticle interaction and the particles’ shape, colloids can act as building blocks that self-assembly into larger structures.

Can we provide the Dutch government with an integrative framework, wherein the various policies can be placed and the need for further measures can be identified?

This thesis investigates how galaxies form and what diversifies the evolutionary histories of galaxies.

Leiden University and the Ministry of Infrastructure and Water Management are involved in a collaboration in the form of a research project titled 'Data-Driven Risk Assessment in Infrastructure Networks'

The aim of this project was to estimate emissions from lead products-in-use for the past, the present and the future and assess the development of toxicological risks associated with these products.

This work describes several studies into the electroreduction of carbon dioxide (CO2RR), both regarding mechanistical aspects and catalyst stability considerations. Mechanistic insights into carbon-carbon bond formation on a silver catalyst are described in Ch 2, were we find an acetaldehyde-like surface…

In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…

Promotores: W. Jiskoot, F. Ossendorp

To limit the effects of climate change, global average temperature since pre-industrial measurements are to be kept well below 2 °C preferably even at 1.5 °C.

Promotie

In 2022 is Leiden European City of Science. In dit jaar zal Leiden het Europese kennispodium zijn, met een programma vol wetenschap, kunst en cultuur. En natuurlijk doen ook de geesteswetenschappen hieraan mee. Maak kennis met het facultaire kernteam.

Lezing

Development of scenarios for 2050 detailed in an IO framework

The basic program comprises a total of twelve courses organized by the Research School, that have been purpose-developed for training and support of PhD students and Research MA students who specialize in Medieval Studies (history, art history, and literary history, in particular).

This initiative is intended to support generative research collaborations between and among scholars located in different geographical regions who wish to pursue focused, joint projects in any area of the study of religion.

Has the industrial sector in China effectively been decarbonizing in recent years, across different regions and subsectors, and is it plausible that it will reduce its CO2 emissions in conformity with national and internationally pledged emission goals?

How can we broaden youth participation in STEM Learning

De onderzoeksgroep Corporate Governance en Strategie onderzoekt hoe, met wie en voor wie een onderneming waarde creëert/vastlegt, met als doel de praktijk en beleidsmakers te informeren over kwesties rondom bestuur. De onderzoeksgroep focust zich op het duale karakter van de onderneming. Namelijk als…

The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.

The research presented in this thesis concerns one of the most important questions in software engineering of our time: how can we make sure that software is free from memory safety bugs?

The aims of the project are to: further clarify 'inhibition by safety'; explore and describe all possible sagety factors, with a special focus on the primary human safety source: social connectedness; reviewing prolonged stress responses without stressors.

What is the optimal design of sandy solutions for sustainable climate change adaption, from an ecological, biophysical and societal point of view?

This project investigates the rich linguistic history of the crucial language groups in East Africa and includes a search for words that indicate earlier lost languages. These outcomes, combined with recent archaeological and genetic research, will contribute to a new understanding of East Africa’s…

This report investigates the different approaches in the authorization process of GMOs for commercial use in the European Union and the United States of America. Three main aspects are considered and analyzed as potential causes of differences in the authorization process of GMOs for commercial use.…

What performance criteria does a new technology have to fulfill in order to be added to the list of future energy options and what constraints exist in terms of broad market penetration?

Are there significant differences among the environmental impacts resulting form the production of Asian aquaculture commodities and what are the main causes for these?

Did the Jochids leave their mark on the Grand Duchy, taking into account that the Lithuanian state was one of the main successor states of the Great Horde in the 16thCentury?

Promotores: F.H.J. Redig, W.T.F. den Hollander

Promotie

Wiskunde en Natuurwetenschappen, Centrum voor Milieuwetenschappen Leiden (CML)

Wiskunde en Natuurwetenschappen, Centrum voor Milieuwetenschappen Leiden (CML)

Peter Pels, affiliated with the Institute of Cultural Anthropology of Leiden University, is one of the researchers. Together with Birgit Meyer (UU), he will lead the work package 'Heritage and the Question of Conversion'.

Grensverleggend geschiedenis leren.

Course Program 2023-2024

Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC), Leids Instituut voor Onderzoek in de Natuurkunde (LION)

Last month, on March 19th, Leiden Law School hosted the first Law, AI & Digitalisation Meetup, a collaborative initiative organised by the departments of Public Law, Civil Law, eLaw, and Business Studies. The afternoon event featured engaging pitch sessions, informative poster presentations, and networking…

The Digital Medievalist has recently created a curated Zenodo community, called the Digital Medieval Webinar Repository (DMWR) to house recorded presentations on medieval topics.

Students Practicing Citizen Journalism

Promotor: H.J.M. de Groot

How does the management of Elephant Marsh Fishery in Malawi relate to wider contexts of policies, theories and regions? And how can the current management system be adapted to achieve long-term sustainability of the fishery?

Parasitaire wormen en maagbacteriën onderdrukken immuunreacties, zoals allergische reacties. Parasitoloog Hermelijn Smits en longarts Christian Taube van het LUMC proberen van deze micro-organismen te leren.