1,929 zoekresultaten voor “part 1521 1990 disease women” in de Publieke website
-
Improving care for red blood cell alloimmunized pregnant women
Promotie
-
Translational pharmacokinetics-pharmacodynamics in zebrafish: integration of experimental and computational methods
The zebrafish is a promising vertebrate model organism in early drug discovery and development.
-
Visual analytics for spatially-resolved omics data at single cell resolution: Methods and Applications
The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…
-
Lipid signaling and inflammation: metabolomics for better diagnosis and treatment strategy
Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…
-
Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.
-
B cell modulation in atherosclerosis
Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.
-
Development of personalized health monitoring using ultra-weak photon emission based on systems medicine concepts
Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk
-
Exploring chemical space in covalent and competitive glycosidase inhibitor design
Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency
-
Involvement of host and bacterial factors in Agrobacterium-mediated transformation
Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.
-
Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.
-
Experience and Voice: Library of Colombian Women Writers - Symposium & Workshop
Symposium & Workshop
-
Isogeny graphs, modular polynomials, and applications
This thesis has three main parts. The first part gives an algorithm to compute Hilbert modular polynomials for ordinary abelian varieties with maximal real multiplication. Hilbert modular polynomials of a given level b give a way of finding all of the abelian varieties that are b-isogeneous to any given…
-
Synthetic peptides as tools in chemical immunology
This thesis has described novel synthetic methods to produce a variety of (glyco)peptides and their application in the study of various immunological processes.
-
COMET. Human Subject Research and Medical Ethics in Colonial Southeast Asia
Investigating epistemic and ethical practices in medical experimentation on humans in the colonial period in Southeast Asia.
-
Nieuwe stoffen remmen ontsteking in het brein
Leidse chemisch biologen, onder leiding van dr. Mario van der Stelt, hebben stoffen ontdekt die ontstekingsprocessen in de hersenen kunnen verminderen. Daarmee is een eerste stap gezet in de ontwikkeling van potentiële geneesmiddelen voor de behandeling van hersenziekten zoals de ziekten van Alzheimer…
-
Cultural Anthropologist Peter Pels part of research team into colonial collections
Peter Pels, affiliated with the Institute of Cultural Anthropology of Leiden University, is one of the researchers. Together with Birgit Meyer (UU), he will lead the work package 'Heritage and the Question of Conversion'.
-
Archief
Benieuwd naar de afgelopen lezingen? In het archief bewaren wij de presentaties en eventuele verslagen van onze lezingen.
-
Capillary Electrophoresis-Mass Spectrometry based Metabolomics Approaches for Volume-restricted Applications
Metabolomics is a powerful tool that can provide a comprehensive insight into the complexity of human biology and the pathophysiology of diseases. By analyzing the metabolome, which refers to the complete set of small (endogenous) molecules (with a mass <1500 Da) present within a given biological system,…
-
‘Please Give Me My Divorce’ An Ethnography of Muslim Women and the Law in Senegal
Promotie
-
NWO-beurs drijft zoektocht naar duurzame productie antibiotica
De kans om een nieuw, spannend onderwerp te onderzoeken. Dat is hoe Lennart Schada von Borzyskowski zijn succesvolle beursaanvraag voor de NWO XS-beurs noemt. Deze 50.000 euro zal de onderzoeker van het Instituut Biologie Leiden (IBL) spenderen aan het ontwikkelen van een nieuwe methode om op duurzame…
-
miniaturised assays for structure-resolved lipidomics in metabolic disease
Promotie
-
Global Fields and Their L-functions
Artin L-functions associated to continuous representations of the absolute Galois group G_K of a global field K capture a lot of information about G_K as well as arithmetic properties of K.
-
Species Literacy: The perception and cultural portrayal of animals
In his dissertation Michiel Hooykaas outlines the results of six empirical research projects focused at biodiversity awareness in the Netherlands, specifically people’s knowledge about animals.
-
Over de grens van de onrechtmatige daad
Op 12 januari 2022 verdedigde Mirjam Franke het proefschrift 'Over de grens van de onrechtmatige daad'. Het promotieonderzoek is begeleid door prof.mr. A.G. Castermans en prof.mr. J.H. Crijns.
-
Multifaceted role of the complement system in health and disease
Promotie
-
Role of intestinal microbiota in cardio-metabolic disease
Promotie
-
Advanced echocardiographic imaging in valvular and systemic diseases
Promotie
-
Early diagnosis and management of celiac disease in childhood
Promotie
-
Pharmacotherapy and Ventilatory Control in Health and Disease
Promotie
-
Oxidative Stress in Chronic Diseases: Causal Inference from Observational Studies
Promotie
-
Oxidants and antioxidants as targets for cardiovascular disease prevention
Promotie
-
Viral gene therapy approaches for CRB1 retinal disease
Promotie
-
Genetics and Life Course Epidemiology of Cardiometabolic Disease
Promotie
-
4D-Flow MRI of Aortic and Valvular Disease
Promotie
-
Developmental cell lineage dynamics in Bicuspid Aortic Valve disease
Promotie
-
glycocalyx; a diagnostic and therapeutic target in cardiometabolic diseases
Promotie
-
Metabolomics to predict progression in chronic kidney disease
Promotie
-
Collegegeld
De hoogte van het collegegeld is afhankelijk van een aantal dingen: uit welk land je afkomstig bent, welke opleiding je doet en of je eerder al eens een opleiding hebt afgerond.
-
Wireless Random-Access Networks and Spectra of Random Graph
This thesis is divided into two parts. In Part I we study metastability properties of queue-based random-access protocols for wireless networks. The network is modeledas a bipartite graph whose edges represent interference constraints. In Part II we study spectra of inhomogeneous Erdős-Rényi random…
-
Non-invasive biomarkers for inflammatory skin diseases: towards systems dermatology
Promotie
-
Origami metamaterials : design, symmetries, and combinatorics
In the first part of this thesis we study the geometry of folding patterns.
-
Mechanical Response of Foams: Elasticity, Plasticity, and Rearrangements
Promotor: M.L. van Hecke
-
A monodromy criterion for existence of Neron models and a result on semi-factoriality
In the first part, we introduce a new condition, called toric-additivity, on a family of abelian varieties degenerating to a semi-abelian scheme over a normal crossing divisor.
-
Bayesian Inference for Gaussian Models
This dissertation studies the Asymptotics of Bayesian nonparametric inference for Gaussian linear models.
-
Innovation and stasis
The name ‘Jambi flora’ refers to fossil plants found as part of a rock formation from the Early Permian (296 million years old), located in the Jambi Province of Sumatra, Indonesia.
-
From data to models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua
-
Unraveling temporal processes using probabilistic graphical models
Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.
-
Boosting the host immune system to fight tuberculosis
New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.
-
Evolutionary adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
-
Transcultural Health Care Utilisation in Serengeti of Tanzania: Towards Applied Ethnoscience in Public Health Management
The research provides insight into disease behavior in both rural and semi-urban areas in Serengeti in Tanzania.