One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.

This thesis covers various applications of topology in condensed matter physics and quantum information.

In 2015, CML published over 70 papers, contributed to the United Nations conference on climate change in Paris, won awards and advised the Dutch government on the safe use of pesticides. CML awarded 11 PhDs and taught students from all over the world how to contribute to sustainability. We wish you…

Discover the master program Health, Ageing and Scoiety at Leiden University and contribute to a future proof health care system. Read more.

Call for Application for a Monumenta Germaniae Historica (MGH) Fellowship

Promotor: S.J. Edixhoven Co-promotor: L. van Geemen, P. Parent

Promotor: Prof.dr. M. Franx, Co-Promotor: Rychard Bouwens

Description of Atlas of the surfacewater concentrations of pesticides in the Netherlands, a pilotstudy.

Nicotinamide adenine dinucleotide (NAD+) is the substrate used for the introduction of the ubiquitous and highly dynamic PTM in which either one or multiple adenosine diphosphate ribose (ADPr) moieties are covalently attached to a nucleophilic side chain of an specific amino acid in the target protein…

This thesis contributes to studying primordial cosmology theories and their detectability in future observations.

The research presented in this thesis concerns one of the most important questions in software engineering of our time: how can we make sure that software is free from memory safety bugs?

Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee

What would be the environmental performance of the Carbon4PUR technology at industrial scale in the future?

Does the presence of Ring-necked parakeets negatively influence feeding and feeding behaviour of native bird species on artificial bird feeders and if so, what are possible solutions?

What happens to electrical waves that have to cross gaps in insulation material around nerves in the human body

Promotor: S.J. Edixhoven, Co-promotor: K.J. Batenburg

Promotor: Prof.dr. E.J.J. Groenen, Co-Promotor: M. Huber

Promotor: S.J. Edixhoven

In this work the reconstruction of a tau neutrino signal in the KM3NeT detector is discussed.

Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)

Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…

Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen

Promotores: F.H. van Lunteren, F.P. Israel

Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)

n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.

Including modelling as part of software development appears to have various benefits.

Promotor: J.N. Kok, Co-promotor: M.S. Lew

Big Science, commonly defined as conventional science made big in three dimensions, namely organizations, machines, and politics, brings a plethora of different stakeholders together, often for a long period of time. This includes policymakers, scientists, (scientific) managers as well as local “host”…

One of the most important puzzles in modern astrophysics is the nature of dark matter.

In this thesis we study bistable reaction-diffusion equations on lattice domains.

Molecular materials have been a subject of interest in fundamental research and applications for decades, and have been studied as bulk crystals, (thin) films and as individual molecules, due to the large variety in their properties. This dissertation explores pentacene crystals near the two-dimensional…

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

Promotie

Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.

Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.

With the dramatic growth of the image data on the web, there is an increasing demand of the algorithms capable of understanding the visual information automatically.

The radio sky harbours both galactic and extragalactic sources of arcminute- to degree-scale emission of various physical origins. To discover extragalactic diffuse emission in the Cosmic Web beyond galaxy clusters, one must image low–surface brightness structures amidst a sea of brighter compact fore-…

Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea

Promotor: Prof.dr. G.R. de Snoo

Promotie

Promotores: Prof.dr. H.J.M. de Groot, Prof.dr. J. Matysik (Universitaet Leipzig)

This work has described synthetic strategies towards well-defined structures resembling capsular polysaccharide (CPS) fragments, CPS mimics, teichoic acid (TA) fragments as well as a third-generation ring-closing tandem metathesis (RCM) linker to better exploit the potential of automated synthesis.

Promotores: S.F. Portegies Zwart, E. M. Rossi

Promotores: Prof.dr. F.S. de Boer, Prof.dr. J.J.M.M. Rutten (Radboud Universiteit Nijmegen)

My work focuses on a class of astronomical objects called protoplanetary disks.