4,689 zoekresultaten voor “russian and science linguistics” in de Publieke website
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Dynamics and regulation of the oxidative stress response upon chemical exposure
The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…
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multi-objective optimization of software architecture design: method, tool, and application
Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich
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The electrochemical reduction of dioxygen and hydrogen peroxide by molecular copper catalysts
The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…
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Using mouse models to uncover genes driving tumorigenesis and therapy resistance in human breast cancer
To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.
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MOOC The Importance and Power of Music in our Society
Online cursus The Importance and Power of Music in our Society
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Mind the gap: gas and dust in planet-forming disks
Promotores: Prof.dr. E.F. van Dishoeck, Prof.dr. C.P. Dullemond
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The mixed Ax-Lindemann theorem and its applications to the Zilber-Pink conjecture
Promotores: Prof.dr. S.J. Edixhoven, Prof.dr. E. Ullmo (University Paris-Sud)
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Mechanisms and consequences of horizontal gene transfer in cell wall-deficient cells of Kitasatospora viridifaciens
The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…
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Low energy electron transmission through layered materials and chiral organic films
In this Ph.D. thesis we study the interaction of low energy electrons with thin materials, namely layered materials (graphene, hexagonal boron nitride, molybdenum disulfide) and organic films. At these low energies the quantum mechanical wavelength of the electron wave function is in the order of a…
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against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf
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Algorithm selection and configuration for Noisy Intermediate Scale Quantum methods for industrial applications
Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.
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P450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography
Promotor: Prof.dr. M. Ubbink
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Development of automatic image analysis methods for high-throughput and high-content screening
Promotor: Prof.dr. B. van de Water
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Discovery and exploitation of the transcriptional regulatory system of pectinases in Aspergillus niger
Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.
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Giant unilamellar vesicles: An efficient membrane biophysical tool and its application in drug delivery studies
Promotor: A. Kros
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Magnetic imaging of spin waves and magnetic phase transitions with nitrogen-vacancy centers in diamond
The elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information carriers in a new generation of electronic devices, (almost) free of electric currents.
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Hydrocarbons in interstellar ice analogues: UV-vis spectroscopy and VUV photochemistry
Promotor: Prof.dr. H.L.V. Linnartz
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Molecular inheritance from cloud to disk: a story of complex organics and accretion shocks
Stars like the sun are born in large molecular clouds existing from gas and dust. During the formation process, the chemical composition of the material can be altered drastically by the changing physical conditions.
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Microcoil MRI of Plants and Algae at Ultra-High Field: An exploration of metabolic imaging
This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).
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Involvement of host and bacterial factors in Agrobacterium-mediated transformation
Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.
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Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis
Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.
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Effects of slug herbivory on seedling recruitment in Brassica napus and B. rapa
Promotor: Prof.dr. P.G.L. Klinkhamer, Co-Promotor: T.J. de Jong
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Witnessing the Process of Bacterial Cell Death: Novel Antimicrobials and Their Mechanisms of Action
This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…
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Two-photon multifocal microscopy for in vivo single-molecule and single-particle imaging
In this thesis we investigated the ability of two-photon multifocal microscopy for single-molecule microscopy in live cells and organisms.
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Enumeration and Simulation of Lattice Polymers as Models for Compact Biological Macromolecules
Promotores: H. Schiessel, G.T. Barkema
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Kaiser Lentelezingen: De geologie van het zonnestelsel: de prachtige planetaire paralellen van tastbare gesteenten en inspirerende landschappen
Lezing
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Kaiser Lentelezingen: Astrochemie
Lezing
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These kind of words: number agreement in the species noun phrase in international academic English
Op 3 september promoveert Adrian Stenton. Het Leiden University Centre for Linguistics feliciteert Adrian!
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Instrumentos musicais nas línguas bantu e a herança no português do Brasil
Op 25 september promoveert Alzenir Mendes Martins de Menezes. Het Leiden University Centre for Linguistics feliciteert Alzenir!
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A Sociolinguistic Study of an Ewe-based Youth Language of Aflao, Ghana
Op 26 september promoveert Cosmas Rai Amenorvi. Het Leiden University Centre for Linguistics feliciteert Cosmas!
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Studies in Tocharian verbal morphology relevant to the cladistic position of Tocharian in Indo-European
Op 24 september promoveert Louise S. Friis. Het Leiden University Centre for Linguistics feliciteert Louise!
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Online Course Introduction to Comparative Indo-European Lingistics
Indo-European is the name of the language family to which English belongs, along with many sub-families such as Germanic languages and Romance languages. In this course, you will delve into the structure and origins of these branches, the oldest languages belonging to the language family, linguistic…
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Jonge wetenschappers vinden elkaar bij Young Faculty of Science
Universitair docent, het kan een vrij solitair bestaan zijn. Deze wetenschappers hebben vaak nog geen eigen onderzoeksgroep en beschikken nog niet over het uitgebreide netwerk van universitaire hoofddocenten of hoogleraren. En dat is precies wat de Young Academy Leiden beoogt te veranderen. De eerste…
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Genomics driven metabolomics novel strategies for the discovery and identification of secondary metabolites
Promotor: T. Hankemeier, Co-promotor: R.J. Vreeken
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Prediction Sets via Parametric and Nonparametric Bayes: with Applications in Pharmaceutical Industry
This thesis consists of five chapters on how to construct prediction sets for different types of data and models in a parametric or nonparametric Bayesian paradigm.
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Environmental assessment and guidance for the future offshore wind energy development
This thesis aims to address offshore wind energy (OWE)-related environmental impacts.
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Conspiracy thinking and social media use are associated with ability to detect deepfakes
Deepfakes zijn video’s die gemanipuleerd zijn om twee personen te verwisselen. Ze kunnen moeilijk te onderscheiden zijn van de originele video’s. In onze studie laten we zien dat mensen die meer complotdenken en mensen die meer gebruikmaken van social media beter zijn in het herkennen van deepfakes.
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Gastonderzoekers
Het Leiden University Centre for Linguistics (LUCL) verwelkomt gastonderzoekers van buiten de Universiteit Leiden die onderzoek willen doen aan het instituut.
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Vervolgopleidingen
Wil je een volledige academische opleiding? Dan ga je na je bachelor door met een masteropleiding. Met een masterdiploma op zak heb je meer kans op een baan op academisch niveau. Na afronding krijg je de titel Master of Arts (MA).
- Onderzoeksprojecten
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Making the invisible visible: paramagnetic NMR and the transient protein complex
Promotor: Prof.dr. M. Ubbink
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additional signals on genes: on the combination of DNA mechanics, genetics and translation speed
DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.
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Stable single molecules for quantum optics and all-optical switches
Promotor: Prof.dr. M.A.G.J. Orrit
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there yet? Advances in anytime-valid methods for hypothesis testing and prediction
Statistical considerations guide the design and implementation of the experiments that scientists perform. For instance, in a clinical trial about a the efficacy of a treatment, its effect in a certain minimum amount of patients has to be observed in order to make confident assertions about the efficacy…
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galaxy clusters collide: the impact of merger shocks on cluster gas and galaxy evolution
Promotor: Prof.dr. H.J.A. Rottgering
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Effect of Nanoparticles on Microbial Catabolism and Community Structure using Biolog techniques
1. To what extent do metallic NPs added to soil extractions change the activity, abundance, or community composition of microbes? 2. How do the effects of metallic NPs on soil microbes differ from the effects of the ions shedding from corresponding NPs?
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Metabolomic characterization of plant exudates and their correlation with plant defense systems
Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.
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Multi-omics studies of the control of growth and antibiotic production of Streptomyces
Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).
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Controlling growth and morphogenesis of the industrial enzyme producer Streptomyces lividans
Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom
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Thaddeus BergéFaculteit der Sociale Wetenschappen