Promotores: Prof.dr. G.A. van der Marel, M. van Heel

Bicarbonate buffer is largely found in nature due to its ability to regulate pH variations around neutral values. As the pH changes, so does the speciation of the buffer.

Op 25 november 2018 verdedigde Laurens de Hoog zijn proefschrift 'De prioriteitsregel in het vermogensrecht'. Het promotieonderzoek is begeleid door promotor prof. mr. W.G. Huijgen.

The unit residue group, to which the present thesis is devoted, is defined using the norm-residue symbol, which Hilbert introduced into algebraic number theory in 1897.

This thesis considers multi-prover commitment schemes whose security is based on restrictions on the communication between the provers.

Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats

Promotor: Prof.dr. P.G.L. Klinkhamer, Co-Promotor: T.J. de Jong

This thesis presents pioneering work on the panchromatic emission of some of the most luminous galaxies in the early Universe: star forming galaxies and active galactic nuclei.

Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros

In this PhD-thesis several new and existing data science application are described that are particularly focused on applications for tax administrations.

Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

This dissertation presents new cryptographic protocols, which can be divided into two families.

Promotores: G.W. Canters, T.J. Aartsma

Promotores: Prof.dr.G.R. de Snoo and Dr. R. Heijungs

Promotor: Roeland M.H. Merks

Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…

Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.

Human civilization consumes a huge amount of fossil fuels, which has resulted in an atmospheric CO2 level which has not been higher in over 800 millennia.

Op 1 februari 2018 verdedigde Charlotte Vrendenbarg haar proefschrift getiteld ‘Proceskostenveroordeling en toegang tot de rechter in IE-zaken. Regelingen over proceskosten getoetst aan het EU-recht’. Het promotieonderzoek is begeleid door promotoren prof. mr. H.J. Snijders en prof. mr. D.J.G. Visse…

Promotor: Prof.dr. G.R. de Snoo

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

This thesis mainly extends the theory of positive operators on Riesz spaces to a setting of pre-Riesz spaces.

Promotor: R. Tijdeman, Co-promotor: H.J.J. te Riele

This thesis is comprised of three chapters covering the theme of studying semistable varieties by looking at their dual combinatorial objects.

Continuous optimization is never easy: the exact solution is always a luxury demand and the theory of it is not always analytical and elegant.

The growing demand of energy indicates that global energy resources in the form of fossil fuels will not be sufficient in the future. In order to solve potential future energy problems development of a sustainable hydrogen economy is highly desirable.

CML rapport 192

The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.

This thesis describes the Multi-site All-Sky CAmeRA (MASCARA), which consists of two small robotic telescope designed to detect exoplanets around the brightest stars in the sky.

This thesis describes the use of bioorthogonal proteins in immunological settings. It provides an introduction towards the field of protein modification, which was used throughout the thesis for the expression of proteins containing unnatural amino acids.

Overall dispersion in LCA as result of inherent uncertainties, spread and unrepresentativeness.

Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.

With tomography it is possible to reconstruct the interior of an object without destroying.

Promotores: Prof. dr. G.R. (Geert) de Snoo, Dr. E. (Ester) van der Voet

Promotores: J.A.van Veen, P.L.G.Klinkhamer. Co-promotor: E.E.Kuramae

Visualizing the internal structure is a crucial step in acquiring knowledge about the origin, state, and composition of cultural heritage artifacts. Among the most powerful techniques for exposing the interior of cultural heritage objects is computed tomography (CT), a technique that computationally…

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea

This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…

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How can we, together international experts, define future needs of R+D contributions for innovations in the field of risk-based management of chemicals and products in a global perspective using alternative testing strategies to minimize animal tests?

De belangrijkste casestudy van het project is de culturele geografie van Sakkara, de necropolis van de oud-Egyptische stad Memphis, en de ontwikkeling daarvan.

Neptunus is de achtste planeet vanaf de zon en staat op een afstand van 4,5 miljard kilometer. Hij staat zo ver af van de zon dat het wel 165 jaar duurt voordat Neptunus een rondje om de zon heeft gedraaid. Een dag op Neptunus is korter dan op aarde: in maar 16 uur draait Neptunus een rondje om zijn…

Veldwerkers en Vrouwen in en om Baskenland gaat over vijf Nederlandse taalkundigen die de Baskische taal bestudeerden. Deze heren waren Jonkheer Willem Jan van Eys, dr. C. C. Uhlenbeck, twee van zijn studenten William Rollo en Nicolaas Deen en dr. Rudolf de Rijk.

Dr. Joris Larik, universitair docent vergelijkend, EU- en internationaal recht bij LUC The Hague, is coauteur van het rapport 'UN 2.0: Ten Innovations for Global Governance 75 Years beyond San Francisco'.

Van oerknal tot supergeleiding. In de lange geschiedenis van de universiteit zijn heel wat baanbrekende ontdekkingen gedaan.

Promotie

Een internationaal team van onderzoekers, onder leiding van Leidse sterrenkundigen, heeft voor het eerst scherpe radiokaarten gemaakt van het heelal op lage frequenties. Dankzij een nieuwe kalibratietechniek omzeilden ze de verstoringen van de aardse ionosfeer. Met de nieuwe methode bestudeerden ze…