De incubatietijd (van infectie tot de eerste symptomen) en latente periode (van infectie tot de start van besmettelijkheid) zijn cruciaal voor het informeren van controle maatregelen aan het begin van een infectieziektenuitbraak. Een voorbeeld is de duur van quarantaine voor potentieel geïnfecteerden,…

The development process of any software has become extremely important not just in the IT industry, but in almost every business or domain of research.

Systems with local constraints is a new finding in recent researches on complex systems. The heterogeneous spatial interactions and the temporal dependencies among those numerous units make it difficult to describe by traditional statistical physics.

Cholesterol influences many pathways, including serving as precursor for adrenal steroidogenesis. Imbalance of cholesterol levels has been implicated in several diseases including cardiovascular diseases and its underlying pathology, atherosclerosis.

The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.

Development of an aggregated impact indicator to measure decoupling.

Dissochaeta Blume (Melastomataceae, tribe Dissochaeteae) is well-known as a scrambling plant genus found in Southeast Asia, where it is an inhabitant of the tropical rainforests or evergreen forests.

Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.

This thesis deals with the use of sound in interactions in the context of participatory systems and data sonification. We investigate an interactive environment where participants perceive information of the data through sound elements.

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: J.D.C. Codee

This paper describes the development process of voting behavior in Chile; particularly the relationship between the class voting theory and the theory of cultural post-materialist vote is investigated. This research deals with Chile as a case study, a developing country with a relatively stable democracy…

The challenge of achieving fast quantification in metabolomics is the presence of severe matrix effects during the MS analysis of complex samples.

The work described in this Thesis is focused on the assembly of oligosaccharide fragments derived from a fungal polysaccharide, galactosaminogalactan (GAG) and fragments of the exopolysaccharide Pel, generated by Pseudomonas aeruginosa.

Kim de Jong, Jaime Delgadillo en Michael Barkham bieden waardevolle inzichten in hun boek 'Routine Outcome Monitoring and Feedback in Psychological Therapies' over hoe therapeuten en stagiaires feedback kunnen gebruiken om beslissingen over behandelingen te onderbouwen en uiteindelijk de resultaten…

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

Promotor: G.A. van der Marel, Co-promotor: D.C. Codée

Promotor: Thomas Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto

Promotor: G.R. de Snoo

Promotores: Prof.dr. H Lenstra, Prof.dr. A Facchini (Padova University)

Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel

Continuous optimization is never easy: the exact solution is always a luxury demand and the theory of it is not always analytical and elegant.

The use of increasingly large and diverse datasets to guide urban climate action has implications for how, and by whom, local governments are held accountable.

Promotor: R. Gill, Co-promotor: P. Massart

Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…

In this thesis we will explore the use of fuzzy systems theory for applications in bioinformatics.

How can we bridge the gap between experts and the general public?

The work in this thesis has been focused on two subjects. The first is the assembly of alginate oligosaccharides and the generation of building blocks for the enzymatic synthesis of alginate, and the second is the total synthesis of large fragments of the zwitterionic SP1 polysaccharide.

Balsaminaceae is a diverse plant family characterized by a huge floral morphological diversity.

In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.

The Central European University is a graduate-level, English-language university with a multi-disciplinary Medieval Department that offers MA and PhD programs in Late Antique, Medieval and Early Modern Studies as well as in Cultural Heritage Studies. Deadline: 1 February 2023.

Kidney transplantation is a major advance of modern medicine. This course will give you state of the art updates about what used to be an experimental, risky, and very limited treatment option more than 50 years ago and is now routinely performed in many countries worldwide.

1) Assess the trends in supply and production status of these critical minerals and mineral products worldwide and Europe’s dependence including on intermediate products such as permanent magnets, RE based super alloys, batteries, polishing compounds, phosphors, catalysts etc. 2) Trace the entire value…

Laboratory, observation and modeling work on the dissociation of polycyclic aromatic hydrocarbons in interstellar environments and the formation of new molecular species through the fragmentation process.

De masterspecialisatie History, Arts and Culture of Asia van de Universiteit Leiden is gericht op studenten die één of meer landen of regio’s in pre-modern, modern of hedendaags Azië willen bestuderen vanuit de geesteswetenschappen.

De masteropleiding Politics, Culture and National Identities, 1789 to the Present van de Universiteit Leiden geeft je de mogelijkheid om op een nieuwe manier Europese politiek en identiteit te onderzoeken.

De masterspecialisatie Politics, Society and Economy of Asia van de Universiteit Leiden is gericht op studenten die één of meer landen of regio’s van modern of hedendaags Azië willen bestuderen vanuit het perspectief van de sociale wetenschappen.

Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf

The main objective of this thesis was to develop clinically relevant survival models for patients with high-grade soft tissue sarcoma of the extremities, in particular the development and validation of prediction models for use in clinical practice.

Promotor: Prof.dr.ir. J.G.E.M. Fraaije, Co-promotor: A. Kros

In this thesis we study quantum transport phenomena on the nanometer scale, in two classes of materials: topological insulators with induced superconductivity and graphene superlattices.

This thesis explores interfacial conductance and electric field-effects in LaAlO3/SrTiO3 heterostructures.

This thesis focuses on the study of transient and variable radio sources in the universe.

This Thesis shows discoveries in non-linear astrochemical kinetics as well as a deeper analysis of dark clouds chemistry.

The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles.

In 2018, the number of mobile phone users will reach about 4.9 billion. Assuming an average of 5 photos taken per day using the built-in cameras would result in about 9 trillion photos annually.

The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.

This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.

To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman