Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…

This thesis focused on the exploration of monolayer graphene as a membrane in direct methanol fuel cell (DMFC) applications, with improvements achieved through plasma exposure or damage- free chemical functionalization.

The database research community has made tremendous strides in developing powerful database engines that allow for efficient analytical query processing.

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

A new type of tripodal squaramide-based supramolecular hydrogels is developed and studied.

Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.

Humans share meaning through language. Over time, repeated interactions have shaped languages into forms that match our cognitive preferences, making them structured, expressive, easy to learn, and ultimately, meaningful.

In this thesis we have discussed several parameters that affect the electrochemical conversion of enviromentaly harmful molecules such as nitrates and carbon dioxide to more valuable and less deleterious compounds, in order to cast light onto the mechanism of the reaction to achieve an efficient and…

Promotor: M. Ubbink, Co-Promotor: R. T. Dame

This dissertation is part of a broader research project that revolves around unraveling the evolution of balanced lethal systems.

In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.

BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.

The main goal of this thesis is to achieve advanced control of binding properties in bis-pyrrolic and macrocyclic pyrrolic receptors by light.

With an emphasis on developing novel miktoarm star polymers termed PeptoMiktoStars, this thesis leverages asymmetric polymeric polypept(o)ide frameworks to advance their effectiveness in delivering hydrophobic drugs and nucleic acids.

The aim of this thesis was to study phage infection in Streptomyces, focused on cell wall-deficient cells. Bacteriophages (or phages in short) attach to the cell wall of bacteria after which they replicate and lyse the host cell.

Promotor: Prof.dr. J.N. Kok, Co-promotor: F.J. Verbeek

Despite being the second largest transmembrane protein family after GPCRs, the SLC superfamily has only gained significant attention in early drug development over the past decade.

Promotor: W.Th.F. den Hollander, Co-promotor: F.R. Nardi

In this thesis we study products of linear error correcting codes.

Almost all bacteria are enveloped by a cell wall that provides cellular protection.

In the past decade many population studies have been performed with the Atacama Large Millimeter/submillimeter Array (ALMA) to understand the bulk properties of protoplanetary disks around young stars. These population studies mostly consisted of low mass stars, with relatively few of the disks around…

The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.

In this thesis, we have studied cell images from two types of cells, including pollen grains and the immune cells, neutrophils. These images are captured using a bright field microscope and a confocal microscope.

A structural investigation of coiled coil peptides used as membrane fusogens, mimicing naturally occuring coiled-coil fusion proteins. Synthetic modifications have been made to alter lipid attachment, secondary structure and to insert photoactive azobenzene moieties for active control over coiled coil…

Soil biodiversity is of great importance for the maintenance of multifunctionality in terrestrial ecosystems.

Promotor: B. van de Water, Co-promotor: E.H.J. Danen

The main focus of this thesis is the behaviour of two-dimensional materials, namely (anti)-ferromagnetic materials in the first two chapters, which show topological phases, and energetic square ice in the third and fourth chapter.

Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…

The research group Science Communication and Society aims to understand how science communication works to improve the interaction between science and society. Central themes are ‘Bridging the gap between experts and the general public’ and ‘Evaluating Science Communication’.

In this thesis, we have used numerical approaches to study the effects of translational symmetry breaking on strange metallic systems as realised by the holographic duality⁠.

One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.

When a star is born in our Galaxy, it is quite likely that it has formed within a massive cluster, which hosts numerous high-mass stars bathing their lower mass neighbours in UV radiation.

Data Science (DS) and Artificial Intelligence (AI) are omni-present and have the potential to be incorporated in various fields. However, in order to live up to this expectation, a good understanding of the techniques, their implications and limitations is required. In this minor you develop insights…

Are you interested in studying Data Science & Artificial Intelligence in Leiden? Would you like to know more about this Bachelor programme at Leiden University? Do you have some last questions that only a student can answer? Then sign up for the Experience Day!

Plastics are an intrinsic part of our society. Annually, 400Mt of plastics are produced of which roughly 40% is discarded within a year.

Promotor: Prof.dr. H.V.J. Linnartz

Studievoorlichting

Studievoorlichting

Het Pre-University College start dit najaar met een nieuw programma in Den Haag. Afgelopen donderdag werd dit feestelijk gevierd met de 22 Haagse vwo-scholieren die het traject gaan volgen. Ze krijgen vanaf nu vaardighedenlabs, colleges en gaan een onderzoek doen in Haagse wijken. Ondertussen maken…

Coffeeshopvergunningen mogen tijdelijk worden afgegeven en na deze periode opnieuw worden verstrekt. Dat blijkt uit een uitspraak van de Afdeling bestuursrechtspraak van de Raad van State in het hoger beroep dat de burgemeester van de gemeente Roermond had ingesteld tegen de uitspraak van de rechtbank…

How should jurisdictions, both on the national and on the supra-national level, handle the interaction between public and private law where it regards the regulation of financial markets?

Begin april trad Ton van Haaften aan als nieuwe Dean van de Honours Academy. Het is nu aan hem om de pioniersfase om te zetten in een consolidatiefase en het honoursonderwijs daarmee een standaardonderdeel van het Leidse onderwijsaanbod te maken. Nu zijn eerste maanden er op zitten, blikt hij vooruit…