1,929 zoekresultaten voor “part 1521 1990 disease women” in de Publieke website
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Circulating cells as biomarkers in cardiovascular disease : the difference between men and women
Promotor: J. Kuiper
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Understanding disease suppressive soils
Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.
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Women Writing Mexico (WWM)
Women Writing Mexico (WWM) is a network of women and men concerned with the human rights crisis in Mexico and more specifically, with the impact of structural forms of poverty, everyday violence, and discrimination based on gender, race, social class, and ethnicity, that particularly have an impact…
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LUMC Women College tour
Op 2 oktober 2023 is de eerste editie van de LUMC Women Collegetour georganiseerd. In deze eerste Collegetour sessie, in Bioscoop Trianon in Leiden, is gesproken met transplantatiechirurge Dorottya de Vries. De sessie is gehouden voor tweedejaars studenten Geneeskunde. Onder begeleiding van interviewer…
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Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
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Systems diagnosis of chronic diseases, explored by metabolomics and ultra-weak photon emission
Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang
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glucosylceramide metabolism fundamental studies and applications for Gaucher disease
This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).
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Women and Girls in Science Day
Hoeveel sterren zijn er in het heelal? En hoe komt het dat astronauten kunnen 'zweven' in de ruimte? Op de Universiteit Leiden krijg je op zaterdag 9 februari antwoord op heel veel vragen over sterrenkunde.
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
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Lipidomics study in liver metabolic diseases
The ideas underlying this thesis are that lipidomics may improve the diagnosis of liver metabolic diseases, and can provide further insights into the underlying pathophysiology of these diseases.
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Women as Agents of Change: How has Women’s Political Mobilization Restructured Political Networks and Changed Local Governance?
Gaat de toenemende deelname van vrouwen aan verkiezingen in ruraal India het bestuur verbeteren?
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metabolomics for a systems biology approach to understand Parkinson's disease
Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…
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Preclinical validation of putative targets in cardiovascular and metabolic disease
Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.
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Computational Approaches to Disease, Signaling and Drug Targets
The Minor Computational Approaches to Disease, Signaling and Drug Targets (CADSDT) is focused on fundamental scientific research required for discovery of new drug targets and development of new drugs.
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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Systems diagnosis in chronic disease: prediction and evaluation
Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen
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Single cell mechanics for disease biology and pharmacology
In this thesis, we describe the potential of cell mechanical phenotyping for immune cell characterization, diagnosis, drug testing, as well as treatment of disease.
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Studies on the Pathogenesis of Chronic Kidney Disease
In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…
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Becoming a 'Domestic Worker' or a 'Trailing Spouse': Migrant women, space, body and belonging in Singapore
Promotie
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data-based dynamic modeling to cell-cell signaling and infectious disease spreading
The emergence of complex diseases resulting from abnormal cell-cell signaling and the spread of infectious diseases caused by pathogens are significant threats to humanity. Unraveling the dynamic mechanisms underlying cell-cell signaling and infectious disease spreading is crucial for effective disease…
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Monitoring Alzheimer's disease in transgenic mice with ultra high field magnetic resonance imaging
Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia
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Developing systems for high-throughput screening of infectious diseases using zebrafish
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer
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Investigations on the role of impaired lysosomes of macrophages in disease
The research described in this thesis combines the latest insights in lysosomal function with lysosome centred cell signalling.
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brain connectivity: pharmacological modulation, aging and Alzheimer's disease
Psycholoog Bernadet Klaassens heeft een groot fMRI-onderzoek opgezet naar het effect van medicijnen op hersennetwerken bij veroudering en de ziekte van Alzheimer. Het leverde een unieke dataset op en zicht op een nieuwe methode om medicijnen te ontwikkelen voor patiënten met Alzheimer.
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Intersectional activism: Dutch-Turkish Muslim women “talking back” to securitisation and Islamophobia
Dit artikel onderzoekt de inspanningen van gezaghebbende Turkse maatschappelijke actoren om de stem van moslimvrouwen in Nederland te versterken.
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Fertility and fontanels: women’s knowledge of medicinal plants for reproductive health and childcare in western Africa
Promotor: E.F. Smets, Co-promotor: T.R. van Andel
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stable-isotope labeling: exploring neuronal metabolism related to Parkinson’s disease
The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.
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Insight into the Pathophysiology of Cardiometabolic Diseases using multiple Omics Approaches
Promotie
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Cardiac Computed Tomography Angiography and Characterization of Cardiac Disease
Promotie
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Unravelling the Developmental Origins of Disease: The Power of Mesenchymal Stromal Cells and Monochorionic Twins
Promotie
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Implementation of the EU Preventive Restructuring Directive Part I
In 2019 hebben het Europees Parlement en de Raad de Richtlijn Preventieve Herstructurering (2019/1023) aangenomen, die voorziet in minimale harmonisatie van onder andere preventieve herstructureringskaders (preventive restructuring frameworks, 'PRF'). Dit boek biedt verdiepende analyses van de implementatie…
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biology of common and grey seals along the Dutch coast : stranding, disease, rehabilitation and conservation
Promotores: H.A. Udo De Haes, P.M. Brakefield
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Who is Afraid of More Women in Politics, and Why? An Analysis of Public Opinion in 28 European Countries
In dit artikel bestuderen de auteurs hoe individuele variabelen en variabelen op landelijk niveau op elkaar inwerken bij het beïnvloeden van politieke genderattitudes in Europa.
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Women in International Security Netherlands
Women In International Security (WIIS) is a global organisation dedicated to advancing the leadership and professional development of women in the field of international peace and security. As part of her research on women, peace and security, Dr. Vanessa Newby at the Institute for Security and Global…
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practice for integrated nursing of the elderly with cardiovascular disease in Sumedang, West Java: towards transcultural nursing in Indonesia
The different kinds of cultural perspectives on health and disease of the participants are related to their knowledge, beliefs, values and practices manifested in various forms of lifestyle in Indonesia. The cultural diversity of the population is also related to differences in health behaviour.
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Comorbidities, complications and treatment of childhood obesity
Childhood obesity is an increasing health issue. In the first part of this thesis comorbidities in children with obesity were studied, concerning the diagnostic process and dosing regimens.
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Is asylum bad for men (and better for women)? Changing perspectives on female and male refugees and asylum seekers in the Netherlands in the
Deelproject van
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Immunity in atherosclerosis: novel assays, biomarkers and therapeutic approaches
Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.
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Discovery and characterization of new glucosylated metabolites: pathophysiological consequences
Within this thesis the central stage is taken by the discovery and investigation of transglycosylation of sterols. First, investigation focuses on the development of a method to accurately detect and quantify glucosylated metabolites in biological materials.
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Liesbeth van Vliet ontvangt For Women in Science-beurs
De Leidse onderzoeker Liesbeth Van Vliet krijgt met een beurs de kans om bij het NIAS-instituut te werken aan haar onderzoek naar communicatie met patiënten en hun naasten bij ernstige, vaak ongeneeslijke ziekten. Het beurzenprogramma For Women in Science voor vrouwelijke topwetenschappers is een initiatief…
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Mast cells as immune regulators in atherosclerosis
Cardiovascular syndromes are the major cause of death in Western societies.
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Macrophage activation and cholesterol in atherosclerosis development
Current therapies for patients with atherosclerosis are targeted primarily on reducing blood cholesterol, but this fails to prevent a large number of cardiovascular events.95 In order to identify new therapeutic strategies for treating atherosclerosis, it is important to study the interactions between…
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Putting a spin on it: amyloid aggregation from oligomers to fibrils
This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper
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Publieksevenement International Day of Women & Girls in Science
De Verenigde Naties hebben 11 februari uitgeroepen tot International Day of Women & Girls in Science. De Universiteit Leiden viert deze dag met een open publieksevenement met vrouwelijke topwetenschappers van haar bètafaculteit. Iedereen is welkom vanaf 13:30 uur in het Kamerlingh Onnesgebouw in Lei…
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Omics data integration with genome-scale modelling of dopaminergic neuronal metabolism
Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.
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Call for Papers: Where are the Women after Resolution 1325?
Sinds de Verenigde Naties in 2000 Resolutie 1325 heeft aangenomen over vrouwen, vrede en veiligheid, komt er langzaam maar zeker meer erkenning voor het gegeven dat vrouwen een belangrijke en beslissende rol zouden moeten hebben als het gaat om het voorkomen en oplossen van conflicten. Neem deel aan…
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Experience and Voice: Library of Colombian Women Writers - Symposium & Workshop
Van Soledad Acosta de Samper en Albalucía Angel tot Hazel Robinson Abrahams en Amalialú Posso Figueroa. Tijdens het symposium & de workshop 'Experience and Voice: Library of Colombian Women Writers’ staan de boeken van Colombiaanse schrijfsters uit verschillende historische periodes centraal. De bijeenkomst…
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The interplay between lipids and the immune system in atherosclerosis
Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.
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L’Oréal-UNESCO Women in Science Fellowship toegekend aan Femke Nijboer
Femke Nijboer, universitair docent bij Gezondheids-, medische en neuropsychologie heeft een van de twee Nederlandse fellowships 2015 van L’Oréal-UNESCO Women in Science ontvangen. Dat gebeurde op 24 november bij de KNAW in Amsterdam.