The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.

The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…

To get an idea of the science communication products and research that is possible, a few examples of student projects of recent years are shown below.

Hoe kunnen we sociale cohesie bevorderen in een samenleving die cultureel en religieus divers is?

Geesteswetenschappen, Centre for Linguistics

Geesteswetenschappen, Centre for the Arts in Society

Kom 20 september in de Nacht van Kunst en Kennis naar de Hortus en ontdek de wondere wereld achter medicijnen. Bezoekers kunnen minicolleges volgen, zelf proefjes doen met de kleinste moleculen en ervaren hoe een nieuw geneesmiddel wordt onderzocht.

Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)

Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)

De YAL laat zich horen over beleidskwesties.

The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.

Ontwikkelings- en Onderwijspsychologie verzorgt bachelorcursussen en masterprogramma's.

Vertrouwen en wederkerigheid zijn twee belangrijke sociale gedragingen die adolescenten helpen zich op een succesvolle manier door hun sociale wereld te begeven. In hun artikel in Journal of Research on Adolescence beschrijven Van de Groep, Meuwese, Zanolie, Güroğlu en Crone de ontwikkeling van vertrouwen…

The research described in this thesis focused on the preparation of S/N functionalized carbene ligands and their transition metal complexes, and the exploration of their application as electrocatalysts for proton reduction.

Het LUMC iPSC Hotel biedt de generatie van research grade humane geïnduceerde pluripotente stamcellen (iPSC's) uit verschillende weefselbronnen met behulp van de modernste herprogrammeringstechnieken.

The extensive use of electronic communication channels and other devices has opened new possibilities for collecting data on human behavior. This information is sometimes openly accessible, but largely part of administrative registration systems that are not open to the broader public. The data provides…

Do sustainability values play a role in motivating people to act for biodiversity in successful projects and in successful leadership action? And how could these values be incorporated in current economic valuation methods?

Het HOPES Onderzoek is een van de grootste onderzoeken van dit soort tot nu toe! Door bestaande hersenscans en gegevens van meer dan 4.000 jongeren tussen 14 en 25 jaar te bestuderen, hoopt het projectteam specifieke veranderingen in de hersenen te identificeren die jongeren kwetsbaar maken voor zelfmoordgedachten…

Promotor: Prof.dr. L.J. Slikkerveer

Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

How can prospective LCA be streamlined in a way that its practical application in research and technology development increases?

Promotor: J. Kuiper

This thesis applies data mining in commercial settings in the telecommunications industry.

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

During my PhD research, I studied the photon statistics of light emitted by a microcavity that contains a single quantum dot (QD) on resonance.

The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).

This PhD research sets out to unravel and explain the socio-structural and cultural impacts of oil-industrialization on the local Bakhtiari community in general and the industrial laborers it provided in specific.

Kunnen we van quantum-verrassingen quantum toepassingen maken? Kunnen we het leven onderzoeken en opbouwen vanuit de nano-schaal?

How soil microbial composition impacts structure and composition of the aboveground plant and animal communities?

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

This programme aims to make the digitized archival sources of the Kerala and Tamil Nadu Archives more accessible to Indian and international scholars and to the widest possible audience, in particular to the people of Kerala.

The project

Geesteswetenschappen, Institute for Area Studies

This dissertation presents a new perspective on the life, work and character of the Dutch physical chemist Jacobus Henricus van ’t Hoff, first recipient of the Nobel Prize in Chemistry, and one of the most important and colourful scientists in Dutch history. The image of Van ’t Hoff that emerges from…

De onderzoeksgroep ‘Governance of Crises’ bestudeert verschijnselen, dynamiek en spelers als het gaat om crisisbeheersing. Het Crisis Research Center (CRC) van de Universiteit Leiden maakt deel uit van deze onderzoekgroep.

The main aim of this project is to reveal and unravel the invisible histories of the UN, transcending the dominant Western perspective to recover the historical agency of Global South actors. The research will investigate how the UN has both facilitated and limited their role in shaping global order…

An objective of this research was to achieve direct, well-defined and non-rate-limiting electron transfer between respiratory enzymes and the electrode surface by means of 'Q-wires'.

Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen

We are living in an information era where the amount of image and video data increases exponentially.

De sectie Cognitieve Psychologie draagt bij aan de 3-jarige bacheloropleiding en verzorgt 2 masterspecialisaties.

PUMA aims at composing a geological map of the urban mine of Amsterdam for a selection of metals. Where are main deposits of copper, iron and aluminium located, when will they become available for secondary production, in what state and shape are they?

Medewerkers van de sectie Methodologie & Statistiek zijn lid van verschillende commissies.

Leiden University’s Academic Challenge

Ter ere van de beroemde statisticus Florence Nightingale organiseert het Data Science Research Programme een reeks seminars in samenwerking met LIACS en MI.

In our research protein translocation from Agrobacterium into yeast and plant cells is studied to obtain fundamental insights in the translocation process

The research described in this thesis combines the latest insights in lysosomal function with lysosome centred cell signalling.