1,107 zoekresultaten voor “paddy 1492 1492 disease works” in de Publieke website
-
Urbanization in Indonesia and Its Impact on Non-communicable Diseases
Promotie
-
Aortic valve disease: multimodality imaging for risk stratification and evaluation of therapy
Promotie
-
in acute myocardial infarction and the assessment of valvular heart disease
Promotie
-
Targeting autoimmunity in renal diseases: focus on neutrophil extracellular traps and autoreactive B-cells
Promotie
-
Advanced tools and methods for modeling cardiovascular disease using human pluripotent stem cells
Promotie
-
Genetic and clinical pharmacology studies in GBA1-associated Parkinson's disease
Promotie
-
Multi-modality imaging in ischemic heart disease, arrhythmia and cardiac-mechanics
Promotie
-
Based Pituitary Care, implementing Value Based Health Care in a rare disease
Promotie
-
Optimising neonatal management of haemolytic disease of the foetus and newborn
Promotie
-
closer look: Non-invasive tools for in-depth characterisation of vulvar diseases
Promotie
-
pharmacology of antimicrobials, towards optimized treatment of infectious diseases in hospitalized patients
Promotie
-
miniaturised assays for structure-resolved lipidomics in metabolic disease
Promotie
-
Therapeutic neovascularization for peripheral arterial disease; in vivo models and potential therapeutic factors
Promotie
-
to predictive modeling: cerebrovascular events and chronic kidney disease
Promotie
-
ENIGMA-Anxiety Werkgroep
Samen met wetenschappers van over de hele wereld streeft de ENIGMA-Anxiety Werkgroep ernaar om meer inzicht te krijgen in de neurobiologische karakteristieken van angststoornissen.
-
Hydrogen dissociation on metal surfaces
Promotor: G. J. Kroes
-
Coiled-coil biomaterials for biological applications
This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.
-
Advances in computational methods for Quantum Field Theory calculations
In this work we describe three methods to improve the performance of Quantum Field Theory calculations.
-
Hydrogen dissociation on metal surfaces
Dissociative chemisorption is an important reaction step in many catalytic reactions.
-
Chemical synthesis of fragments of galactosaminogalactan and pel polysaccharides
The work described in this Thesis is focused on the assembly of oligosaccharide fragments derived from a fungal polysaccharide, galactosaminogalactan (GAG) and fragments of the exopolysaccharide Pel, generated by Pseudomonas aeruginosa.
-
Total Synthesis of Alginate and Zwitterionic Sp1 Oligosaccharides
The work in this thesis has been focused on two subjects. The first is the assembly of alginate oligosaccharides and the generation of building blocks for the enzymatic synthesis of alginate, and the second is the total synthesis of large fragments of the zwitterionic SP1 polysaccharide.
-
Chasing cosmic tau neutrinos in the abyss
In this work the reconstruction of a tau neutrino signal in the KM3NeT detector is discussed.
-
ELS Lab meetings
Voor onderzoekers geïnteresseerd in empirisch juridisch onderzoek.
-
Governance and Data Science Group
The extensive use of electronic communication channels and other devices has opened new possibilities for collecting data on human behavior. This information is sometimes openly accessible, but largely part of administrative registration systems that are not open to the broader public. The data provides…
-
Parttime programma
Sinds 2021 is de master ook in deeltijd te volgen, een parttime opleiding van 2-3 dagen per week, waarvan één vaste, verplichte dag op vrijdag.
-
Understanding the Heterogeneity of Corporate Entrepreneurship Programs
In today's volatile market environments, companies must be able to continuously innovate. In this context, innovation does not only refer to the development of new products or business models but often also affects the entire organization, which has to transform its structures, processes, and ways of…
-
elderly in clinical trials: how to define preclinical Alzheimer’s Disease for clinical trial participation
Promotie
-
Remodeling, Myocardial Function and Risk Stratification in Cardiovascular Disease
Promotie
-
autoantibody-positive and autoantibody- negative rheumatoid arthritis during the disease course
Promotie
-
microbiota transplantation and dietary interventions in Inflammatory Bowel Disease; efficacy and challenges for the future
Promotie
-
A joint evaluation of local and systemic disease activity in treated-to- target rheumatoid arthritis
Promotie
-
Unraveling the broad NOTCH3-associated small vessel disease spectrum: from CADASIL to non-penetrance
Promotie
-
Non-invasive biomarkers for inflammatory skin diseases: towards systems dermatology
Promotie
-
Multimodality Imaging in Coronary Artery Disease: Plaque Characterization, Computational Haemodynamic Simulation and Risk Stratification
Promotie
-
Specifiek eiwit in de hoofdrol bij ziekte van Parkinson
Met elektronspins hebben natuurkundigen het bindingsproces onderzocht van het eiwit α-synucleïne, dat wordt geassocieerd met de ziekte van Parkinson. Wat blijkt is dat het eiwit op een verrassend efficiënte manier bindt aan een hersenmembraan. Met deze in Leiden ontwikkelde methode hebben de onderzoekers…
-
Post-doc : Algorithmic Bias in Ageing Societies
Sociale Wetenschappen, Psychologie
-
Starter grant 2
LA cuidadora: Latin American female migration and elderly home-care work in Europe
-
Instituut Biologie Leiden
De natuur is een onuitputtelijke inspiratiebron voor de wetenschappers van het Instituut Biologie Leiden (IBL). Vanuit het streven naar fundamenteel begrip van de natuur zoeken zij naar oplossingen op het gebied van gezondheid en behoud van de biodiversiteit. Het thema van het instituut is ‘Harnessing…
-
The innate immune response against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf
-
Functional analysis of agrobacterium tumefaciens virulence protein VirD5
Supervisor: P.J.J. Hooykaas
-
Parkinson’s protein α-synuclein: membrane interactions and fibril structure
The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.
-
PI3K signaling and adherens junctions in invasive lobular breast cancer
Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.
-
Electrical and magnetic properties of ferritin: electron transport phenomena and electron paramagnetic resonance
Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.
-
Pharmaceutical Aspects of Subvisible Particles in Protein Formulations
Promotor: W. Jiskoot, Co-promotor: A. Hawe
-
Discovery of novel inhibitors to investigate diacylglycerol lipases and α/β hydrolase domain 16A
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
-
The road to insurmountability: Novel avenues to better target CC Chemokine receptors
This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.
-
1,2-cis-glycosylations: method development and synthesis of complex oligosaccharides
Promotor: G.A. van der Marel, Co-promotor: D.C. Codée
-
Image analysis for gene expression based phenotype characterization in yeast cells
Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek
-
Phenotypic screening with 3D cell-based assays
Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.
-
Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink