DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.

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Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

Promotor: G.P. van Wezel, Co-promotor: D. Claessen

Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

We explored the Universe using weak gravitational lensing, a phenomenon that occurs when light from distant galaxies is bent by the gravitational fields of closer cosmic objects, much like how a lens distorts light.

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

Every organisms in the tree of life faces the same challenge: the length of its DNA exceeds the volume of the cell it needs to fit in. Several strategies have evolved to solve this problem, one of them being the expression of proteins that bind and organize the DNA.

Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.

Promotor: Prof.dr. B. van de Water

Control of infectious diseases poses continuous challenges for human health.

The way organisms develop from the initial single-cellular state to a complex final assembly like the human body, and how the final body is maintained throughout life, is one of the greatest mysteries and it’s understanding one of the biggest scientific challenges.

Promotor: Prof.dr. M.L. van Heck, Co-Promotor: B.P. Tighe

Arithmetic geometry concerns the number-theoretic properties of geometric objects defined by polynomials. Mathematicians are interested in the rational solutions to these geometric objects.

The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.

Bacterial biocatalysis constitutes a sustainable alternative for high-value chemicals production by enabling the utilization of renewable feedstocks.

This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.

Promotor: Prof.dr. J. den Hertog

Promotor: J. Zaanen, Co-Promotor: V. Juricic

Promotor: B. van de Water

In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

This dissertation consists of two parts, each of which considers a different research area related to random interval maps. In the first part we are interested in random interval maps that are critically intermittent.

Stars like the sun are born in large molecular clouds existing from gas and dust. During the formation process, the chemical composition of the material can be altered drastically by the changing physical conditions.

In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.

Retorica is overal. In de Tweede Kamer, in de rechtbank, en in de collegezaal; maar ook op de markt, op Twitter, en op Facebook. Mensen proberen elkaar steeds weer te overtuigen met argumenten, te verleiden met emoties, en te imponeren met een gunstige zelfpresentatie. De minor Retorica bestudeert de…

Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe

Promotores: S.F. Portegies Zwart, E. M. Rossi

Voltammetry plays a crucial role in modern scientific research by offering valuable insights into the electrochemical properties of materials, with wide-ranging applications in fields such as materials science, energy storage, corrosion studies, and sensor development.

In this PhD study, I aim to deepen our understanding of the influence of major mycorrhizal types, namely arbuscular mycorrhizae (AM) and ectomycorrhizae (EM), on the global soil carbon cycle and their potential distribution changes under future environmental shifts.

Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…

We find ourselves in an era of transition, not just towards a more computing- and data-driven society but also away from unsustainable fossil fuels as an energy source.

Leiden is een echte studentenstad met een sfeervol en compact centrum waar je alles vindt wat je in je studentenleven nodig hebt. Den Haag is een internationale studentenstad en biedt jou een mooie mix voor een rijk en gevarieerd studentenleven.

In some condensed matter systems, such as the surface of a 3D topological insulator, the electrons are effectively massless and we must necessarily use the massless Dirac equation to describe them.

Studievoorlichting

Leiden is een echte studentenstad en heeft alles in huis om van jouw studententijd een onvergetelijke tijd te maken. En als internationaal georiënteerde studentenstad biedt Den Haag jou een mooie mix voor een geweldige studententijd.

Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans

The origin and evolution of galaxies are closely tied to the cyclic feedback processes between stars and the interstellar medium (ISM).

In recent decades, climate change has led to more frequent and severe drought events, causing serious consequences such as increased forest mortality and significant crop yield losses. Understanding how drought affects plants, especially economically important herbaceous species, is crucial for predicting…

Hot astrophysical plasma is ubiquitous in the Universe, from comets in our Solar system to the largest scale structures -- the cosmic web filaments. These hot plasmas, with the temperature of a few millions of degrees, are often observed in the X-ray wavelength range.

Promotor: T.J. Aartsma, Co-promotor: R.N. Frese

Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

S.S. Kolipaka’s thesis questions and investigates the survival prospects of reintroduced tigers and their offspring’s in the human dominated landscape of Panna tiger reserve in India.

Indicators to measure progress in de-linking economic growth and environmental pressure.

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…

A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.